Which antibiotic should be avoided in developing teeth due to staining effects?

• A. Tooth discoloration and enamel hypoplasia
• B. Gingival hyperplasia
• C. No effect
• D. Periodontal disease

Answer: (A)

Tetracycline antibiotics can permanently discolor teeth when given during tooth development. They bind to calcium in developing teeth and bones, causing permanent tooth staining and, if enamel formation is underway, enamel hypoplasia. Because of this, these drugs are avoided in pregnancy and in children under about eight years old. The statement describing tooth discoloration and enamel hypoplasia directly reflects this staining risk, so it is the best answer. Other options describe conditions unrelated to antibiotic-induced staining (gum overgrowth, no effect, or periodontal disease).