Which enzyme creates a unified strand by joining the lagging strands?

Study for the Manor Preboards Module 2 Test. Use flashcards and multiple choice questions that include hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

Which enzyme creates a unified strand by joining the lagging strands?

Explanation:
Joining the lagging strand fragments to form a continuous DNA strand is done by DNA ligase. During replication, the lagging strand is made in short pieces called Okazaki fragments; DNA ligase seals the nicks between these fragments, creating one intact strand by forming phosphodiester bonds. Helicase unwinds the double helix, primase lays down RNA primers to start each fragment, and DNA polymerase builds the new DNA but cannot connect the fragments itself. DNA ligase is the enzyme that completes the final link, producing a unified strand.

Joining the lagging strand fragments to form a continuous DNA strand is done by DNA ligase. During replication, the lagging strand is made in short pieces called Okazaki fragments; DNA ligase seals the nicks between these fragments, creating one intact strand by forming phosphodiester bonds. Helicase unwinds the double helix, primase lays down RNA primers to start each fragment, and DNA polymerase builds the new DNA but cannot connect the fragments itself. DNA ligase is the enzyme that completes the final link, producing a unified strand.

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