Which organelle is the site of ribosome synthesis?

Study for the Manor Preboards Module 2 Test. Use flashcards and multiple choice questions that include hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

Which organelle is the site of ribosome synthesis?

Explanation:
Ribosome synthesis happens in the nucleolus, a region within the nucleus where ribosomal RNA genes are transcribed and pre-rRNA is processed and assembled with ribosomal proteins. Here, rRNA is made by RNA polymerase I, and the ribosomal proteins imported from the cytoplasm join with this rRNA to form the small and large ribosomal subunits. These subunits mature in the nucleolus and are then exported to the cytoplasm to become functional ribosomes. Other organelles have different roles—mitochondria do house their own ribosomes for some mitochondrial proteins, but the assembly of whole ribosomes occurs in the nucleolus, not in mitochondria, lysosomes, or peroxisomes.

Ribosome synthesis happens in the nucleolus, a region within the nucleus where ribosomal RNA genes are transcribed and pre-rRNA is processed and assembled with ribosomal proteins. Here, rRNA is made by RNA polymerase I, and the ribosomal proteins imported from the cytoplasm join with this rRNA to form the small and large ribosomal subunits. These subunits mature in the nucleolus and are then exported to the cytoplasm to become functional ribosomes. Other organelles have different roles—mitochondria do house their own ribosomes for some mitochondrial proteins, but the assembly of whole ribosomes occurs in the nucleolus, not in mitochondria, lysosomes, or peroxisomes.

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