Which enzyme attaches primers to the 3'-end of the strands?

Study for the Manor Preboards Module 2 Test. Use flashcards and multiple choice questions that include hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

Which enzyme attaches primers to the 3'-end of the strands?

Explanation:
DNA replication needs a starting point with a free 3'-OH to begin DNA synthesis. Primase is the enzyme that lays down short RNA primers, providing that 3'-end from which DNA polymerase can extend and build new DNA. Without these primers, DNA polymerase wouldn’t be able to start synthesizing. The other enzymes have different roles: helicase unwinds the double helix, DNA polymerase adds nucleotides after a primer is in place, and DNA ligase seals gaps once fragments are joined after primer removal.

DNA replication needs a starting point with a free 3'-OH to begin DNA synthesis. Primase is the enzyme that lays down short RNA primers, providing that 3'-end from which DNA polymerase can extend and build new DNA. Without these primers, DNA polymerase wouldn’t be able to start synthesizing. The other enzymes have different roles: helicase unwinds the double helix, DNA polymerase adds nucleotides after a primer is in place, and DNA ligase seals gaps once fragments are joined after primer removal.

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