Which amino acid is the precursor for indole alkaloids?

Study for the Manor Preboards Module 2 Test. Use flashcards and multiple choice questions that include hints and explanations. Prepare thoroughly for your exam!

Multiple Choice

Which amino acid is the precursor for indole alkaloids?

Explanation:
Indole alkaloids get their defining indole ring from tryptophan. In many biosynthetic routes, tryptophan is decarboxylated to tryptamine, and this indole-containing molecule is then built upon to form the wide family of indole alkaloids. The other amino acids listed do not provide the indole nucleus: tyrosine and phenylalanine point toward different alkaloid or phenylpropanoid pathways, and threonine is not a source of the indole skeleton. So, tryptophan is the precursor.

Indole alkaloids get their defining indole ring from tryptophan. In many biosynthetic routes, tryptophan is decarboxylated to tryptamine, and this indole-containing molecule is then built upon to form the wide family of indole alkaloids. The other amino acids listed do not provide the indole nucleus: tyrosine and phenylalanine point toward different alkaloid or phenylpropanoid pathways, and threonine is not a source of the indole skeleton. So, tryptophan is the precursor.

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