How many CO2 molecules are released in one turn of the Krebs cycle?

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Multiple Choice

How many CO2 molecules are released in one turn of the Krebs cycle?

Explanation:
Two CO2 molecules are released per turn of the Krebs cycle. As the two-carbon acetyl group from acetyl-CoA is oxidized, it is released as carbon dioxide in two decarboxylation steps: first when isocitrate is converted to α-ketoglutarate, and again when α-ketoglutarate is converted to succinyl-CoA. This loss of carbon dioxide regenerates the four-carbon oxaloacetate, which can accept another acetyl-CoA to continue the cycle.

Two CO2 molecules are released per turn of the Krebs cycle. As the two-carbon acetyl group from acetyl-CoA is oxidized, it is released as carbon dioxide in two decarboxylation steps: first when isocitrate is converted to α-ketoglutarate, and again when α-ketoglutarate is converted to succinyl-CoA. This loss of carbon dioxide regenerates the four-carbon oxaloacetate, which can accept another acetyl-CoA to continue the cycle.

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