Dextran can be used as a plasma expander.

• A. Dextran can be used as a plasma expander
• B. Inulin can be used as a plasma expander
• C. Chitin can be used as a plasma expander
• D. Cellulose can be used as a plasma expander

Answer: (A)

Plasma expanders work by increasing the volume of fluid kept inside the blood vessels. Dextran is a synthetic polysaccharide that acts as a colloid, meaning its large molecules stay in the intravascular space and raise the blood’s oncotic pressure. This draws water from the surrounding tissues back into the vessels, producing a rapid and more sustained increase in circulating volume compared with crystalloids. Dextran has been used for resuscitation, although its use is tempered by risks like interference with coagulation and potential hypersensitivity.

In contrast, the other polymers mentioned aren’t used as plasma expanders because they don’t provide the same intravascular colloidal effect. Inulin is mainly used to test kidney function, not to expand plasma volume. Chitin and cellulose are structural polymers with little to no role as intravascular volume expanders.